Product Data Sheet
Zonisamide sodium
Catalog No. A31478
Zonisamide sodium is a potent carbonic anhydrase inhibitor, effectively targeting hCA II and hCA V with Kis of 35.2 nM and 20.6 nM, respectively. This compound exhibits neuroprotective properties by promoting anti-apoptotic mechanisms and enhancing the expression of manganese superoxide dismutase (MnSOD). Additionally, Zonisamide sodium has been shown to upregulate Hrd1, contributing to improved cardiac function in animal models of cardiac hypertrophy. Its diverse biological activities make it suitable for investigations related to seizures, Parkinson's disease, and cardiovascular research.
Chemical Information
| Catalog Num | A31478 |
|---|---|
| M. Wt | 234.21 |
| Formula | C8H7N2NaO3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 68291-98-5 |
| Synonyms | AD 810 sodium; CI 912 sodium |
| SMILES | O=S(CC1=NOC2=C1C=CC=C2)([NH-])=O.[Na+] |
Biological Activity
| Description | Zonisamide sodium is a potent carbonic anhydrase inhibitor, effectively targeting hCA II and hCA V with Kis of 35.2 nM and 20.6 nM, respectively. This compound exhibits neuroprotective properties by promoting anti-apoptotic mechanisms and enhancing the expression of manganese superoxide dismutase (MnSOD). Additionally, Zonisamide sodium has been shown to upregulate Hrd1, contributing to improved cardiac function in animal models of cardiac hypertrophy. Its diverse biological activities make it suitable for investigations related to seizures, Parkinson's disease, and cardiovascular research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
