Product Data Sheet
Spisulosine-d3
Catalog No. A31481
Spisulosine-d3 is a deuterium-labeled derivative of Spisulosine, known for its role as a stable isotope. This marine-derived compound exhibits potent antiproliferative activity, effectively inhibiting the growth of prostate cancer cell lines PC-3 and LNCaP. The mechanism of action involves the accumulation of intracellular ceramide and activation of protein kinase C zeta (PKCζ), leading to apoptotic induction in these cancer cells. It serves as a valuable tool for investigating the mechanisms of tumor growth and apoptosis in cancer research.
Chemical Information
| Catalog Num | A31481 |
|---|---|
| M. Wt | 288.53 |
| Formula | C18H36D3NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1246298-31-6 |
| Synonyms | ES-285-d3 |
| SMILES | [2H]C([2H])([2H])[C@H](N)[C@H](O)CCCCCCCCCCCCCCC |
Biological Activity
| Description | Spisulosine-d3 is a deuterium-labeled derivative of Spisulosine, known for its role as a stable isotope. This marine-derived compound exhibits potent antiproliferative activity, effectively inhibiting the growth of prostate cancer cell lines PC-3 and LNCaP. The mechanism of action involves the accumulation of intracellular ceramide and activation of protein kinase C zeta (PKCζ), leading to apoptotic induction in these cancer cells. It serves as a valuable tool for investigating the mechanisms of tumor growth and apoptosis in cancer research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
