Product Data Sheet
KTX-582 intermediate-1
Catalog No. A31483
KTX-582 intermediate-1 is a crucial intermediate in the synthesis of KTX-582, serving as a key component for antibody-drug conjugate (ADC) preparation. KTX-582 functions as an IRAK4 degrader, effectively inducing apoptosis with DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. This compound is instrumental for research applications focused on targeting IRAK4-related pathways and exploring therapeutic strategies in various cancers.
Chemical Information
| Catalog Num | A31483 |
|---|---|
| M. Wt | 326.41 |
| Formula | C16H22O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 845508-29-4 |
| Synonyms | |
| SMILES | CCOC([C@@H](CC1)CC[C@@H]1OS(=O)(C2=CC=C(C=C2)C)=O)=O |
Biological Activity
| Description | KTX-582 intermediate-1 is a crucial intermediate in the synthesis of KTX-582, serving as a key component for antibody-drug conjugate (ADC) preparation. KTX-582 functions as an IRAK4 degrader, effectively inducing apoptosis with DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. This compound is instrumental for research applications focused on targeting IRAK4-related pathways and exploring therapeutic strategies in various cancers. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
