Product Data Sheet
Thalidomide-O-amido-C8-NH2 hydrochloride
Catalog No. A31527
Thalidomide-O-amido-C8-NH2 hydrochloride functions as an E3 ligase ligand-linker conjugate, incorporating the Thalidomide-derived cereblon ligand along with a suitable linker. This compound is instrumental in the development of proteolysis-targeting chimeras (PROTACs), enabling targeted protein degradation in research applications. Its structural features facilitate selective binding to E3 ligases, making it a valuable tool in drug discovery and cellular function studies.
Chemical Information
| Catalog Num | A31527 |
|---|---|
| M. Wt | 494.97 |
| Formula | C23H31ClN4O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2415263-07-7 |
| Synonyms | |
| SMILES | O=C(NCCCCCCCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.Cl |
Biological Activity
| Description | Thalidomide-O-amido-C8-NH2 hydrochloride functions as an E3 ligase ligand-linker conjugate, incorporating the Thalidomide-derived cereblon ligand along with a suitable linker. This compound is instrumental in the development of proteolysis-targeting chimeras (PROTACs), enabling targeted protein degradation in research applications. Its structural features facilitate selective binding to E3 ligases, making it a valuable tool in drug discovery and cellular function studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
