Product Data Sheet
Thalidomide-O-amido-C6-NH2
Catalog No. A31557
Thalidomide-O-amido-C6-NH2 serves as an E3 ligase ligand-linker conjugate, featuring a thalidomide-based cereblon ligand with an integrated linker. This compound is utilized in the synthesis of PROTACs (proteolysis-targeting chimeras), facilitating targeted protein degradation pathways. Its unique structure allows for selective degradation of specific proteins, making it valuable in cancer research and other therapeutic applications.
Chemical Information
| Catalog Num | A31557 |
|---|---|
| M. Wt | 430.45 |
| Formula | C21H26N4O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1950635-13-8 |
| Synonyms | Cereblon Ligand-Linker Conjugates 11; E3 Ligase Ligand-Linker Conjugates 25 |
| SMILES | O=C(NCCCCCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O |
Biological Activity
| Description | Thalidomide-O-amido-C6-NH2 serves as an E3 ligase ligand-linker conjugate, featuring a thalidomide-based cereblon ligand with an integrated linker. This compound is utilized in the synthesis of PROTACs (proteolysis-targeting chimeras), facilitating targeted protein degradation pathways. Its unique structure allows for selective degradation of specific proteins, making it valuable in cancer research and other therapeutic applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
