Product Data Sheet
Thalidomide-Piperazine-Piperidine
Catalog No. A31564
Thalidomide-Piperazine-Piperidine is a synthesized E3 ligase ligand-linker conjugate that targets cereblon, a key component in the ubiquitin-proteasome system. This compound incorporates a Thalidomide-based ligand and a piperazine-piperidine linker, making it suitable for use in PROTAC (proteolysis-targeting chimeras) technology. Its design facilitates targeted degradation of specific proteins, providing valuable insight into protein regulation and function in various biological contexts. Thalidomide-Piperazine-Piperidine is ideal for research applications involving targeted protein degradation and cellular signaling pathways.
Chemical Information
| Catalog Num | A31564 |
|---|---|
| M. Wt | 425.48 |
| Formula | C22H27N5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2229716-11-2 |
| Synonyms | |
| SMILES | O=C1C(CCC(N1)=O)N2C(C3=C(C=CC(N4CCN(CC4)C5CCNCC5)=C3)C2=O)=O |
Biological Activity
| Description | Thalidomide-Piperazine-Piperidine is a synthesized E3 ligase ligand-linker conjugate that targets cereblon, a key component in the ubiquitin-proteasome system. This compound incorporates a Thalidomide-based ligand and a piperazine-piperidine linker, making it suitable for use in PROTAC (proteolysis-targeting chimeras) technology. Its design facilitates targeted degradation of specific proteins, providing valuable insight into protein regulation and function in various biological contexts. Thalidomide-Piperazine-Piperidine is ideal for research applications involving targeted protein degradation and cellular signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
