Product Data Sheet
PI3Kα-IN-6
Catalog No. A31628
PI3Kα-IN-6 is a selective inhibitor of the phosphoinositide 3-kinase alpha (PI3Kα) pathway. This compound demonstrates significant anticancer activity by promoting the generation of reactive oxygen species (ROS), leading to a decrease in mitochondrial membrane potential (MMP) and subsequently inducing apoptosis in cancer cells. PI3Kα-IN-6 is valuable for research focused on cancer therapeutics and the exploration of PI3K signaling in cell survival and proliferation.
Chemical Information
| Catalog Num | A31628 |
|---|---|
| M. Wt | 410.27 |
| Formula | C16H15IN2OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2272894-14-9 |
| Synonyms | |
| SMILES | COC1=CC=C(C=C1)SCC2=C(N=C3C=CC(C)=CN32)I |
Biological Activity
| Description | PI3Kα-IN-6 is a selective inhibitor of the phosphoinositide 3-kinase alpha (PI3Kα) pathway. This compound demonstrates significant anticancer activity by promoting the generation of reactive oxygen species (ROS), leading to a decrease in mitochondrial membrane potential (MMP) and subsequently inducing apoptosis in cancer cells. PI3Kα-IN-6 is valuable for research focused on cancer therapeutics and the exploration of PI3K signaling in cell survival and proliferation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
