Product Data Sheet

ASK1-IN-4

Catalog No. A31727

main product photo
ASK1-IN-4 is a selective inhibitor of Apoptosis Signal-regulating Kinase 1 (ASK1), demonstrating an IC50 of 0.2 μM. This compound effectively interacts with the ATP-binding site of ASK1, leading to the modulation of apoptotic signaling pathways. ASK1-IN-4 is primarily utilized in research focused on apoptosis regulation, oxidative stress response, and related therapeutic investigations.
Chemical Information
Catalog NumA31727
M. Wt452.34
FormulaC18H14BrNO4S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1427538-26-8
Synonyms
SMILESBrC(C=C1)=CC=C1C2=CC=C(O2)/C=C3C(N(C(S/3)=S)CCCC(O)=O)=O
Biological Activity
DescriptionASK1-IN-4 is a selective inhibitor of Apoptosis Signal-regulating Kinase 1 (ASK1), demonstrating an IC50 of 0.2 μM. This compound effectively interacts with the ATP-binding site of ASK1, leading to the modulation of apoptotic signaling pathways. ASK1-IN-4 is primarily utilized in research focused on apoptosis regulation, oxidative stress response, and related therapeutic investigations.
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