Product Data Sheet
L-Asparagine-15N2,d8
Catalog No. A31734
L-Asparagine-15N2,d8 is a stable isotope-labeled form of the essential amino acid L-Asparagine. This compound serves as a substrate for the enzyme L-Asparaginase, known for its anti-leukemic properties through the depletion of asparagine and glutamine. L-Asparaginase induces apoptosis in leukemic cells by inhibiting RNA and DNA synthesis, particularly in cancer cells with low expression of asparagine synthetase. Additionally, L-Asparagine can be utilized as a biomarker in research applications focused on childhood acute lymphoblastic leukemia.
Chemical Information
| Catalog Num | A31734 |
|---|---|
| M. Wt | 142.15 |
| Formula | C4D815N2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1217473-37-4 |
| Synonyms | |
| SMILES | [2H][15N]([2H])C(C([2H])([2H])[C@@]([15N]([2H])[2H])([2H])C(O[2H])=O)=O |
Biological Activity
| Description | L-Asparagine-15N2,d8 is a stable isotope-labeled form of the essential amino acid L-Asparagine. This compound serves as a substrate for the enzyme L-Asparaginase, known for its anti-leukemic properties through the depletion of asparagine and glutamine. L-Asparaginase induces apoptosis in leukemic cells by inhibiting RNA and DNA synthesis, particularly in cancer cells with low expression of asparagine synthetase. Additionally, L-Asparagine can be utilized as a biomarker in research applications focused on childhood acute lymphoblastic leukemia. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
