Product Data Sheet
Imipramine-d4
Catalog No. A31746
Imipramine-d4 is a deuterated form of Imipramine, a tricyclic antidepressant that primarily acts as a serotonin transporter inhibitor with an IC50 of 32 nM. This compound demonstrates significant biological activities, including inhibition of Fascin1, which contributes to its antitumor effects. Additionally, Imipramine has been shown to stimulate autophagy in U-87MG glioma cells and induce apoptosis in HL-60 cells. Its neuroprotective and immunomodulatory properties make it a valuable reagent for research in cancer biology and neuropharmacology.
Chemical Information
| Catalog Num | A31746 |
|---|---|
| M. Wt | 284.43 |
| Formula | C19H20D4N2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 96705-18-9 |
| Synonyms | |
| SMILES | CN(C)CCCN1C2=C([2H])C=C([2H])C=C2CCC3=CC([2H])=CC([2H])=C31 |
Biological Activity
| Description | Imipramine-d4 is a deuterated form of Imipramine, a tricyclic antidepressant that primarily acts as a serotonin transporter inhibitor with an IC50 of 32 nM. This compound demonstrates significant biological activities, including inhibition of Fascin1, which contributes to its antitumor effects. Additionally, Imipramine has been shown to stimulate autophagy in U-87MG glioma cells and induce apoptosis in HL-60 cells. Its neuroprotective and immunomodulatory properties make it a valuable reagent for research in cancer biology and neuropharmacology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
