Product Data Sheet

NTR 368

Catalog No. A31808

main product photo
NTR 368 is a peptide derived from the p75 neurotrophin receptor (p75NTR), specifically corresponding to residues 368-381 of the human protein. This compound exhibits a propensity to form alpha-helices in the presence of micellar lipids, enhancing its interaction with cellular membranes. NTR 368 serves as a potent inducer of neural apoptosis, making it a valuable tool for studying neurodegenerative processes and the mechanisms underlying neuronal cell death in research applications.
Chemical Information
Catalog NumA31808
M. Wt1565.86
FormulaC69H124N22O19
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.197230-90-3
Synonyms
SMILES[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)C)=O)[C@@H](C)O)=O)CC(C)C)=O)CC(O)=O)=O)C)=O)CC(C)C)=O)CC(C)C)=O)C)=O)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)(C(N[C@H](C(N[C@@H](CCC(N)=O)C(N)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N
Biological Activity
DescriptionNTR 368 is a peptide derived from the p75 neurotrophin receptor (p75NTR), specifically corresponding to residues 368-381 of the human protein. This compound exhibits a propensity to form alpha-helices in the presence of micellar lipids, enhancing its interaction with cellular membranes. NTR 368 serves as a potent inducer of neural apoptosis, making it a valuable tool for studying neurodegenerative processes and the mechanisms underlying neuronal cell death in research applications.
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