Product Data Sheet
Cinnamtannin D1
Catalog No. A31815
Cinnamtannin D1 is a polyphenolic compound recognized for its anti-inflammatory properties, primarily through its immunosuppressive effects. It modulates the Th17/Treg balance by inhibiting AHR expression, subsequently downregulating p-STAT3/RORγt and promoting Treg differentiation via p-STAT5/Foxp3. Cinnamtannin D1 has demonstrated significant protective effects against apoptosis and oxidative stress in INS-1 cells and primary murine islets exposed to palmitic acid. Its efficacy in the collagen-induced arthritis model underscores its potential for research in rheumatoid arthritis.
Chemical Information
| Catalog Num | A31815 |
|---|---|
| M. Wt | 864.76 |
| Formula | C45H36O18 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 97233-06-2 |
| Synonyms | |
| SMILES | O[C@H]1[C@](OC2=CC(O)=C3)(C(C=C4)=CC(O)=C4O)OC(C=C5O)=C(C(O[C@@H]6C(C=C7)=CC(O)=C7O)=C5[C@H](C(C(O)=C8)=C(O[C@H](C(C=C9)=CC(O)=C9O)[C@H]%10O)C(C%10)=C8O)[C@H]6O)[C@@]1([H])C2=C3O |
Biological Activity
| Description | Cinnamtannin D1 is a polyphenolic compound recognized for its anti-inflammatory properties, primarily through its immunosuppressive effects. It modulates the Th17/Treg balance by inhibiting AHR expression, subsequently downregulating p-STAT3/RORγt and promoting Treg differentiation via p-STAT5/Foxp3. Cinnamtannin D1 has demonstrated significant protective effects against apoptosis and oxidative stress in INS-1 cells and primary murine islets exposed to palmitic acid. Its efficacy in the collagen-induced arthritis model underscores its potential for research in rheumatoid arthritis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
