MXC-017
Catalog No. A31822

MXC-017 is a potent apoptosis inducer that effectively penetrates the blood-brain barrier (BBB) and selectively targets Vimentin (VIM). This compound has demonstrated the ability to inhibit radiation-induced glioma stem cell formation while promoting G0/G1 cell cycle arrest and apoptosis. With minimal off-target effects and negligible cytotoxicity, MXC-017 has been shown to significantly enhance median survival in glioblastoma mouse models when used in conjunction with radiation therapy, making it a valuable tool for cancer research.
Chemical Information
| Catalog Num | A31822 |
|---|---|
| M. Wt | 397.49 |
| Formula | C21H23N3O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3037024-97-5 |
| Synonyms | |
| SMILES | O=C(NCC1=CC=C(S(=O)(N2CCCCC2)=O)C=C1)N3C4=CC=CC=C4C=C3 |
Biological Activity
| Description | MXC-017 is a potent apoptosis inducer that effectively penetrates the blood-brain barrier (BBB) and selectively targets Vimentin (VIM). This compound has demonstrated the ability to inhibit radiation-induced glioma stem cell formation while promoting G0/G1 cell cycle arrest and apoptosis. With minimal off-target effects and negligible cytotoxicity, MXC-017 has been shown to significantly enhance median survival in glioblastoma mouse models when used in conjunction with radiation therapy, making it a valuable tool for cancer research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


