Product Data Sheet

PTG-0861

Catalog No. A31833

main product photo
PTG-0861 is a selective inhibitor of histone deacetylase 6 (HDAC6) with an IC50 value of 5.92 nM. This compound effectively induces apoptosis, making it a valuable tool for research in acute myeloid leukemia, multiple myeloma, and other hematological malignancies. Its specificity towards HDAC6 positions it as a promising candidate for studies aimed at understanding epigenetic regulation in cancer.
Chemical Information
Catalog NumA31833
M. Wt360.24
FormulaC15H9F5N2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2494082-34-5
Synonyms
SMILESO=C(NCC1=CC=C(C(NO)=O)C=C1)C2=C(F)C(F)=C(F)C(F)=C2F
Biological Activity
DescriptionPTG-0861 is a selective inhibitor of histone deacetylase 6 (HDAC6) with an IC50 value of 5.92 nM. This compound effectively induces apoptosis, making it a valuable tool for research in acute myeloid leukemia, multiple myeloma, and other hematological malignancies. Its specificity towards HDAC6 positions it as a promising candidate for studies aimed at understanding epigenetic regulation in cancer.
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