Product Data Sheet
Apoptosis inducer 14
Catalog No. A31875
Apoptosis Inducer 14 is a potent chemotherapeutic agent that initiates both intrinsic and extrinsic apoptosis pathways through the activation of P53. Exhibiting IC50 values of 193.93 μg/mL in A549 cells, 6.76 μg/mL in HCT116 cells, and 222.67 μg/mL in HF84 cells, this compound is a valuable tool for research focusing on cancer cell apoptosis and therapeutic efficacy. Applications include investigating mechanisms of cancer cell death and developing novel cancer treatments.
Chemical Information
| Catalog Num | A31875 |
|---|---|
| M. Wt | 459.46 |
| Formula | C27H17N5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2750370-67-1 |
| Synonyms | |
| SMILES | O=C(/C(C#N)=C/C1=CN(C2=CC=CC=C2)N=C1C3=CC=C([N+]([O-])=O)C=C3)C4=CNC5=C4C=CC=C5 |
Biological Activity
| Description | Apoptosis Inducer 14 is a potent chemotherapeutic agent that initiates both intrinsic and extrinsic apoptosis pathways through the activation of P53. Exhibiting IC50 values of 193.93 μg/mL in A549 cells, 6.76 μg/mL in HCT116 cells, and 222.67 μg/mL in HF84 cells, this compound is a valuable tool for research focusing on cancer cell apoptosis and therapeutic efficacy. Applications include investigating mechanisms of cancer cell death and developing novel cancer treatments. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
