Product Data Sheet
Apoptosis inducer 24
Catalog No. A31918
Apoptosis Inducer 24 targets the apoptosis pathway to inhibit proliferation in gastric cancer cells, with an IC50 ranging from 1.2 to 4.8 μM. This compound causes cell cycle arrest at the G2/M phase, induces apoptosis in the BGC-823 cell line, and disrupts mitochondrial function. Additionally, Apoptosis Inducer 24 demonstrates significant antitumor efficacy in murine models, exhibiting a favorable safety profile with an LD50 of 91.2 mg/kg.
Chemical Information
| Catalog Num | A31918 |
|---|---|
| M. Wt | 899.96 |
| Formula | C55H70BNO9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2763063-09-6 |
| Synonyms | |
| SMILES | O=C1C(C#N)=C[C@]2([C@]([H])(C1(C)C)CC[C@](C)(C2=CC3=O)[C@]4([C@]3([C@]5([C@@](C(OCCCCOC(C6=CC=C(C=C6)OCC7=CC=C(C=C7)B8OC(C)(C(C)(O8)C)C)=O)=O)(CC4)CCC(C)(C5)C)[H])[H])C)C |
Biological Activity
| Description | Apoptosis Inducer 24 targets the apoptosis pathway to inhibit proliferation in gastric cancer cells, with an IC50 ranging from 1.2 to 4.8 μM. This compound causes cell cycle arrest at the G2/M phase, induces apoptosis in the BGC-823 cell line, and disrupts mitochondrial function. Additionally, Apoptosis Inducer 24 demonstrates significant antitumor efficacy in murine models, exhibiting a favorable safety profile with an LD50 of 91.2 mg/kg. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
