Product Data Sheet
L-Asparagine-4-13C monohydrate
Catalog No. A31996
L-Asparagine-4-13C monohydrate is a stable isotope-labeled form of the amino acid L-Asparagine. This compound serves as an essential substrate for L-Asparaginase, an enzyme utilized in the treatment of leukemia due to its ability to deplete asparagine, thereby inhibiting RNA and DNA synthesis in lymphoblasts and inducing apoptosis. L-Asparagine-4-13C monohydrate is valuable in research applications, including its use as a biomarker for investigating childhood acute lymphoblastic leukemia and studying metabolic pathways in cancer cells with low asparagine synthetase expression.
Chemical Information
| Catalog Num | A31996 |
|---|---|
| M. Wt | 151.13 |
| Formula | C313CH10N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 286437-12-5 |
| Synonyms | (-)-Asparagine-4-13C monohydrate; Asn-4-13C monohydrate; Asparamide-4-13C monohydrate |
| SMILES | N[13C](C[C@H](N)C(O)=O)=O.[H]O[H] |
Biological Activity
| Description | L-Asparagine-4-13C monohydrate is a stable isotope-labeled form of the amino acid L-Asparagine. This compound serves as an essential substrate for L-Asparaginase, an enzyme utilized in the treatment of leukemia due to its ability to deplete asparagine, thereby inhibiting RNA and DNA synthesis in lymphoblasts and inducing apoptosis. L-Asparagine-4-13C monohydrate is valuable in research applications, including its use as a biomarker for investigating childhood acute lymphoblastic leukemia and studying metabolic pathways in cancer cells with low asparagine synthetase expression. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
