Product Data Sheet

PDE5/HDAC-IN-1

Catalog No. A32026

main product photo
PDE5/HDAC-IN-1 is a dual inhibitor of phosphodiesterase 5 (PDE5) and histone deacetylases (HDAC) with IC50 values of 46.3 nM and 14.5 nM, respectively. This compound has demonstrated the capability to induce cell apoptosis and exhibits significant anticancer activities. PDE5/HDAC-IN-1 is a valuable tool for research in cancer therapeutics and epigenetic modulation.
Chemical Information
Catalog NumA32026
M. Wt553.45
FormulaC27H29BrN4O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2414921-48-3
Synonyms
SMILESO=C1N2[C@@](C3=CC=C(C=C3)Br)([H])C4=C(C[C@]2([H])C(N(C1)CCCCCCC(NO)=O)=O)C5=CC=CC=C5N4
Biological Activity
DescriptionPDE5/HDAC-IN-1 is a dual inhibitor of phosphodiesterase 5 (PDE5) and histone deacetylases (HDAC) with IC50 values of 46.3 nM and 14.5 nM, respectively. This compound has demonstrated the capability to induce cell apoptosis and exhibits significant anticancer activities. PDE5/HDAC-IN-1 is a valuable tool for research in cancer therapeutics and epigenetic modulation.
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SHIPPING AND STORAGE
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