Product Data Sheet

Polyinosinic-polycytidylic acid potassium

Catalog No. A32032

main product photo
Polyinosinic-polycytidylic acid potassium is a synthetic analog of double-stranded RNA that acts as an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors. This reagent is utilized to stimulate innate and adaptive immune responses, serving as an effective vaccine adjuvant while also modifying the tumor microenvironment. Additionally, Polyinosinic-polycytidylic acid potassium can induce apoptosis in cancer cells, making it a valuable compound for cancer research and immunotherapy studies.
Chemical Information
Catalog NumA32032
M. Wt
Formula(C10H13N4O8P)x.(C9H14N3O8P)x.xK
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.31852-29-6
SynonymsPoly(I:C) potassium
SMILESO[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N2C3=C(C(N=CN3)=O)N=C2.O[C@@H]4[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]4N5C(N=C(C=C5)N)=O.[x].[x]
Biological Activity
DescriptionPolyinosinic-polycytidylic acid potassium is a synthetic analog of double-stranded RNA that acts as an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors. This reagent is utilized to stimulate innate and adaptive immune responses, serving as an effective vaccine adjuvant while also modifying the tumor microenvironment. Additionally, Polyinosinic-polycytidylic acid potassium can induce apoptosis in cancer cells, making it a valuable compound for cancer research and immunotherapy studies.
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SHIPPING AND STORAGE
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