Product Data Sheet
Fenobam hydrate
Catalog No. A32078
Fenobam hydrate is a selective mGluR5 antagonist with an IC50 of 84 nM, capable of crossing the blood-brain barrier. It exhibits Kd values of 54 nM and 31 nM for rat and human recombinant mGlu5 receptors, respectively. Fenobam hydrate demonstrates anxiolytic properties, inhibits self-administration behavior in rodent models, and induces apoptosis in cancer cells. This compound is valuable for research in neurological disorders, cancer biology, and addiction studies.
Chemical Information
| Catalog Num | A32078 |
|---|---|
| M. Wt | 284.70 |
| Formula | C11H13ClN4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 63540-28-3 |
| Synonyms | |
| SMILES | O=C(NC1=NC(CN1C)=O)NC2=CC=CC(Cl)=C2.O |
Biological Activity
| Description | Fenobam hydrate is a selective mGluR5 antagonist with an IC50 of 84 nM, capable of crossing the blood-brain barrier. It exhibits Kd values of 54 nM and 31 nM for rat and human recombinant mGlu5 receptors, respectively. Fenobam hydrate demonstrates anxiolytic properties, inhibits self-administration behavior in rodent models, and induces apoptosis in cancer cells. This compound is valuable for research in neurological disorders, cancer biology, and addiction studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
