Product Data Sheet
5-Fluorouracil-13C4,15N2
Catalog No. A32179
5-Fluorouracil-13C4,15N2 is a stable isotope-labeled form of 5-Fluorouracil (5-FU), a uracil analog known for its potent antitumor properties. This compound primarily targets thymidylate synthetase, leading to the inhibition of pyrimidine synthesis and subsequent depletion of intracellular dTTP pools. As a result, 5-Fluorouracil-13C4,15N2 induces apoptosis in cancer cells and may serve as a chemical sensitizer in therapeutic applications. Additionally, it exhibits inhibitory effects against HIV, making it relevant for diverse biological research.
Chemical Information
| Catalog Num | A32179 |
|---|---|
| M. Wt | 136.03 |
| Formula | 13C4H3F15N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 202407-03-2 |
| Synonyms | 5-FU-13C4,15N2 |
| SMILES | O=[13C]1[13C](F)=[13CH][15NH][13C]([15NH]1)=O |
Biological Activity
| Description | 5-Fluorouracil-13C4,15N2 is a stable isotope-labeled form of 5-Fluorouracil (5-FU), a uracil analog known for its potent antitumor properties. This compound primarily targets thymidylate synthetase, leading to the inhibition of pyrimidine synthesis and subsequent depletion of intracellular dTTP pools. As a result, 5-Fluorouracil-13C4,15N2 induces apoptosis in cancer cells and may serve as a chemical sensitizer in therapeutic applications. Additionally, it exhibits inhibitory effects against HIV, making it relevant for diverse biological research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
