Product Data Sheet
Autophagy inducer 2
Catalog No. A32191
Autophagy Inducer 2 is a potent activator of autophagy, primarily targeting cellular mechanisms involved in this critical survival process. It demonstrates significant antiproliferative effects on MCF-7 breast cancer cells, with an IC50 value of 1.31 μM, and markedly reduces colony formation in these cells. By modulating cell-cycle-related proteins such as Cdk-1 and Cyclin B1, Autophagy Inducer 2 effectively induces cell cycle arrest in the G2/M phase. This compound offers valuable insights for research in breast cancer therapy and the regulation of autophagy.
Chemical Information
| Catalog Num | A32191 |
|---|---|
| M. Wt | 650.94 |
| Formula | C41H58N6O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2684238-37-5 |
| Synonyms | |
| SMILES | C[C@]12[C@@]([C@]3(C(C4=CC5=NC=CN=C5C(C)=C4C=C3)=CC1)C)(CC[C@@]6([C@@]2([H])C[C@@](C)(CC6)NC(N7CCN(C8CCN(CC8)C)CC7)=O)C)C |
Biological Activity
| Description | Autophagy Inducer 2 is a potent activator of autophagy, primarily targeting cellular mechanisms involved in this critical survival process. It demonstrates significant antiproliferative effects on MCF-7 breast cancer cells, with an IC50 value of 1.31 μM, and markedly reduces colony formation in these cells. By modulating cell-cycle-related proteins such as Cdk-1 and Cyclin B1, Autophagy Inducer 2 effectively induces cell cycle arrest in the G2/M phase. This compound offers valuable insights for research in breast cancer therapy and the regulation of autophagy. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
