Product Data Sheet
LVTX-8
Catalog No. A32272
LVTX-8 is a peptide toxin derived from Lycosa vittata that targets lung cancer cells through specific signaling pathways. It exhibits potent anticancer and anti-metastatic activities, characterized by strong cytotoxic effects that induce apoptosis while inhibiting proliferation, invasion, and migration of these cells. Research applications include its use in understanding tumor growth inhibition and metastasis in preclinical models, such as A549/H460 xenograft mice. LVTX-8's mechanism involves modulation of P53 hypoxia pathways and integrin signaling, making it a valuable tool for cancer biology research.
Chemical Information
| Catalog Num | A32272 |
|---|---|
| M. Wt | 2849.46 |
| Formula | C135H226N36O31 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2197957-07-4 |
| Synonyms | |
| SMILES | C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CCCCN)=O)CO)=O)CC(C)C)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCCCN)=O)C)=O)CC(C)C)=O)=O)CCCCN)=O)=O)CC(C)C)=O)CC(N)=O)=O)CCCCN)=O)=O)CC(C)C)=O)=O)CCCCN)=O)CC(C)C)=O)C)=O)[C@@H](C)O)=O)CC(C)C)=O)NC([C@H]([C@H](CC)C)N)=O)C=3C=4C(NC3)=CC=CC4 |
Biological Activity
| Description | LVTX-8 is a peptide toxin derived from Lycosa vittata that targets lung cancer cells through specific signaling pathways. It exhibits potent anticancer and anti-metastatic activities, characterized by strong cytotoxic effects that induce apoptosis while inhibiting proliferation, invasion, and migration of these cells. Research applications include its use in understanding tumor growth inhibition and metastasis in preclinical models, such as A549/H460 xenograft mice. LVTX-8's mechanism involves modulation of P53 hypoxia pathways and integrin signaling, making it a valuable tool for cancer biology research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
