Product Data Sheet
Apoptosis inducer 25
Catalog No. A32351
Apoptosis Inducer 25 is a potent apoptosis inducer that specifically targets cell proliferation. It effectively inhibits the growth of BGC-823 cells with an IC50 of 0.37 μM, leading to cell cycle arrest in the G2/M phase. This compound further promotes apoptosis and triggers mitochondrial dysfunction, making it a valuable tool in cancer research. Its favorable pharmacokinetic profile in rat models underscores its potential for further investigation in therapeutic applications.
Chemical Information
| Catalog Num | A32351 |
|---|---|
| M. Wt | 683.87 |
| Formula | C42H53NO7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2763063-15-4 |
| Synonyms | |
| SMILES | O=C1C(C#N)=C[C@]2([C@]([H])(C1(C)C)CC[C@](C)(C2=CC3=O)[C@]4([C@]3([C@]5([C@@](C(OCCCCOC(C6=CC=C(C=C6)O)=O)=O)(CC4)CCC(C)(C5)C)[H])[H])C)C |
Biological Activity
| Description | Apoptosis Inducer 25 is a potent apoptosis inducer that specifically targets cell proliferation. It effectively inhibits the growth of BGC-823 cells with an IC50 of 0.37 μM, leading to cell cycle arrest in the G2/M phase. This compound further promotes apoptosis and triggers mitochondrial dysfunction, making it a valuable tool in cancer research. Its favorable pharmacokinetic profile in rat models underscores its potential for further investigation in therapeutic applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
