Product Data Sheet
Perezone
Catalog No. A32354
Perezone is a sesquiterpenoid benzoquinone derived from the roots of Acourtia species, acting as an anticancer and anti-inflammatory agent. It effectively inhibits the proliferation of leukemia cell line K-562 and human glioma cell line U-251, with an IC50 of 6.83 μM. Furthermore, Perezone upregulates the expression of apoptosis-related genes, including caspase 3, 8, and 9, while also exhibiting significant antioxidant and anti-inflammatory properties. This compound is of interest in cancer research and potential therapeutic applications.
Chemical Information
| Catalog Num | A32354 |
|---|---|
| M. Wt | 248.32 |
| Formula | C15H20O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3600-95-1 |
| Synonyms | |
| SMILES | C/C(C)=C\CC[C@H](C1=C(C(C(C)=CC1=O)=O)O)C |
Biological Activity
| Description | Perezone is a sesquiterpenoid benzoquinone derived from the roots of Acourtia species, acting as an anticancer and anti-inflammatory agent. It effectively inhibits the proliferation of leukemia cell line K-562 and human glioma cell line U-251, with an IC50 of 6.83 μM. Furthermore, Perezone upregulates the expression of apoptosis-related genes, including caspase 3, 8, and 9, while also exhibiting significant antioxidant and anti-inflammatory properties. This compound is of interest in cancer research and potential therapeutic applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
