Product Data Sheet

PSB 0474

Catalog No. A32406

main product photo
PSB 0474 (3-phenacyl-UDP) is a selective and potent agonist of the P2Y6 receptor, exhibiting an EC50 of 70 nM. This compound modulates key biological activities, including the inhibition of cell proliferation and the enhancement of nitric oxide release in astrocytes and microglia. Additionally, PSB 0474 promotes apoptosis in astrocytes, making it a valuable tool for research in neurobiology and cell signaling pathways.
Chemical Information
Catalog NumA32406
M. Wt522.29
FormulaC17H20N2O13P2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.917567-60-3
Synonyms
SMILESO[C@H]([C@@H]1O)[C@@](N(C=CC2=O)C(N2CC(C3=CC=CC=C3)=O)=O)([H])O[C@@H]1CO[P](O[P](O)(O)=O)(O)=O
Biological Activity
DescriptionPSB 0474 (3-phenacyl-UDP) is a selective and potent agonist of the P2Y6 receptor, exhibiting an EC50 of 70 nM. This compound modulates key biological activities, including the inhibition of cell proliferation and the enhancement of nitric oxide release in astrocytes and microglia. Additionally, PSB 0474 promotes apoptosis in astrocytes, making it a valuable tool for research in neurobiology and cell signaling pathways.
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