Product Data Sheet
Tomatine hydrochloride
Catalog No. A32426
Tomatine hydrochloride is a glycoalkaloid derived from the tomato plant (Lycopersicon esculentum Mill.). It has been shown to induce neurotoxicity through mechanisms that are independent of RIP1 kinase and caspases, leading to the upregulation of nuclear apoptosis-inducing factor (AIF) in neuroblastoma cells. Additionally, tomatine hydrochloride inhibits 20S proteasome activity, making it a valuable reagent for research applications in cancer biology and neurodegeneration studies.
Chemical Information
| Catalog Num | A32426 |
|---|---|
| M. Wt | 1070.65 |
| Formula | C50H84ClNO21 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 17605-83-3 |
| Synonyms | α-Tomatine hydrochloride; Lycopersicin hydrochloride; Tomatin hydrochloride |
| SMILES | C[C@@]12[C@]([C@@H]3C)([H])[C@](O[C@@]34CC[C@H](C)CN4)([H])C[C@@]1([H])[C@@](CC[C@]5([H])[C@@]6(CC[C@H](O[C@]([C@@H]([C@@H](O)[C@H]7O[C@@](O[C@H](CO)[C@@H](O)[C@@H]8O[C@@](OC[C@@H](O)[C@@H]9O)([H])[C@@H]9O)([H])[C@@H]8O[C@]([C@@H]([C@@H](O)[C@@H]%10O)O)([H])O[C@@H]%10CO)O)([H])O[C@@H]7CO)C5)C)([H])[C@]6([H])CC2.Cl |
Biological Activity
| Description | Tomatine hydrochloride is a glycoalkaloid derived from the tomato plant (Lycopersicon esculentum Mill.). It has been shown to induce neurotoxicity through mechanisms that are independent of RIP1 kinase and caspases, leading to the upregulation of nuclear apoptosis-inducing factor (AIF) in neuroblastoma cells. Additionally, tomatine hydrochloride inhibits 20S proteasome activity, making it a valuable reagent for research applications in cancer biology and neurodegeneration studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
