Product Data Sheet

Tubulin polymerization-IN-28

Catalog No. A32668

main product photo
Tubulin polymerization-IN-28 is a selective inhibitor of microtubule protein polymerization, primarily targeting tubulin. This compound demonstrates significant anticancer activity by activating NQO1, leading to the release of combretastatin A-4, which promotes apoptosis in tumor cells. Tubulin polymerization-IN-28 is valuable for research applications focused on cancer therapy and the mechanisms of cell death.
Chemical Information
Catalog NumA32668
M. Wt662.77
FormulaC37H46N2O9
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2481404-89-9
Synonyms
SMILESCOC1=CC(/C=C\C2=CC(OC)=C(C=C2)OC(N(CCN(C(CC(C)(C3=C(C(C(C)=C(C3=O)C)=O)C)C)=O)C)C)=O)=CC(OC)=C1OC
Biological Activity
DescriptionTubulin polymerization-IN-28 is a selective inhibitor of microtubule protein polymerization, primarily targeting tubulin. This compound demonstrates significant anticancer activity by activating NQO1, leading to the release of combretastatin A-4, which promotes apoptosis in tumor cells. Tubulin polymerization-IN-28 is valuable for research applications focused on cancer therapy and the mechanisms of cell death.
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SHIPPING AND STORAGE
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