Product Data Sheet
Noscapine-13C,d3
Catalog No. A32696
Noscapine-13C,d3 is a stable isotope-labeled form of noscapine, a phthalideisoquinoline alkaloid known for its potent antitussive properties. This compound primarily acts by engaging sigma opioid receptors and serves as a non-competitive inhibitor of bradykinin. In addition to its antitussive effects, noscapine disrupts microtubule dynamics, induces mitotic arrest, and promotes apoptosis, showcasing significant anticancer, neuroprotective, and anti-inflammatory activities. Its ability to cross the blood-brain barrier makes it suitable for a variety of biological research applications.
Chemical Information
| Catalog Num | A32696 |
|---|---|
| M. Wt | 417.43 |
| Formula | C2113CH20D3NO7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1217680-57-3 |
| Synonyms | |
| SMILES | COC1=C(OCO2)C2=CC3=C1[C@@]([C@]4([H])C5=CC=C(OC)C(OC)=C5C(O4)=O)([H])N(CC3)[13C]([2H])([2H])[2H] |
Biological Activity
| Description | Noscapine-13C,d3 is a stable isotope-labeled form of noscapine, a phthalideisoquinoline alkaloid known for its potent antitussive properties. This compound primarily acts by engaging sigma opioid receptors and serves as a non-competitive inhibitor of bradykinin. In addition to its antitussive effects, noscapine disrupts microtubule dynamics, induces mitotic arrest, and promotes apoptosis, showcasing significant anticancer, neuroprotective, and anti-inflammatory activities. Its ability to cross the blood-brain barrier makes it suitable for a variety of biological research applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
