Tubulin inhibitor 14
Catalog No. A32712

Tubulin Inhibitor 14 targets NQO2 (quinone oxidoreductase 2) and exhibits a potent inhibitory effect with an IC50 of 1.0 μM. It disrupts tubulin polymerization and impedes the formation of capillary-like structures in endothelial cells. This microtubule-destabilizing agent possesses potential tumor-selectivity and exhibits antiangiogenic and vascular-disruptive properties, making it valuable for research in cancer biology and angiogenesis.
Chemical Information
| Catalog Num | A32712 |
|---|---|
| M. Wt | 257.23 |
| Formula | C15H9F2NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2767446-34-2 |
| Synonyms | |
| SMILES | O=C1NC(C2=CC=CC(F)=C2)=CC3=C1C=CC(F)=C3 |
Biological Activity
| Description | Tubulin Inhibitor 14 targets NQO2 (quinone oxidoreductase 2) and exhibits a potent inhibitory effect with an IC50 of 1.0 μM. It disrupts tubulin polymerization and impedes the formation of capillary-like structures in endothelial cells. This microtubule-destabilizing agent possesses potential tumor-selectivity and exhibits antiangiogenic and vascular-disruptive properties, making it valuable for research in cancer biology and angiogenesis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


