Product Data Sheet

Thalidezine

Catalog No. A32724

main product photo
Thalidezine is a selective activator of AMP-activated protein kinase (AMPK), a crucial regulator of cellular energy homeostasis. It has been shown to promote autophagic cell death in anti-apoptotic cancer cells by modulating energy metabolism. Thalidezine serves as a valuable tool for investigating the mechanisms of apoptosis and potential therapeutic interventions in cancer research.
Chemical Information
Catalog NumA32724
M. Wt638.75
FormulaC38H42N2O7
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.18251-36-0
Synonyms
SMILESCOC1=C(O2)C3=C(CCN(C)[C@@]3([H])CC4=CC=C(OC)C(OC5=CC=C(C=C5)C[C@@]6([H])C7=C(CCN6C)C=C(OC)C2=C7)=C4)C(O)=C1OC
Biological Activity
DescriptionThalidezine is a selective activator of AMP-activated protein kinase (AMPK), a crucial regulator of cellular energy homeostasis. It has been shown to promote autophagic cell death in anti-apoptotic cancer cells by modulating energy metabolism. Thalidezine serves as a valuable tool for investigating the mechanisms of apoptosis and potential therapeutic interventions in cancer research.
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