Product Data Sheet
Antiangiogenic agent 7
Catalog No. A32747
Antiangiogenic Agent 7 is an apoptosis inducer known for its ability to stimulate cell death through increased production of Reactive Oxygen Species and inhibition of thioredoxin reductase, an intracellular enzyme. This compound exhibits notable anti-cancer properties, displaying an IC50 range of 0.08-3.5 μM against various cancer cell lines, including HeLa (cervical), PC-3 (prostate), and A549 (non-small cell lung cancer). Additionally, Antiangiogenic Agent 7 demonstrates the potential to inhibit tumor growth in mouse xenograft models, making it a valuable tool for cancer research.
Chemical Information
| Catalog Num | A32747 |
|---|---|
| M. Wt | 647.46 |
| Formula | C24H26AuN3P2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2527888-07-7 |
| Synonyms | |
| SMILES | S=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=C([Au][P@@]4(C5)CN(C6)C[N@]5C[N@@]6C4)C=CC=C3 |
Biological Activity
| Description | Antiangiogenic Agent 7 is an apoptosis inducer known for its ability to stimulate cell death through increased production of Reactive Oxygen Species and inhibition of thioredoxin reductase, an intracellular enzyme. This compound exhibits notable anti-cancer properties, displaying an IC50 range of 0.08-3.5 μM against various cancer cell lines, including HeLa (cervical), PC-3 (prostate), and A549 (non-small cell lung cancer). Additionally, Antiangiogenic Agent 7 demonstrates the potential to inhibit tumor growth in mouse xenograft models, making it a valuable tool for cancer research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
