Product Data Sheet
SSE1806
Catalog No. A32772
SSE1806 is a microtubule/tubulin inhibitor derived from podophyllotoxin, exhibiting notable anticancer and antiproliferative effects. It demonstrates a GI50 range of 1.29-21.15 μM against cancer cell growth, inducing mitotic abnormalities and G2/M phase cell cycle arrest. Additionally, SSE1806 enhances p53 expression and effectively inhibits the growth of colon cancer organoids, while also overcoming multidrug resistance in MDR-1 overexpressing cell lines, making it a valuable tool for cancer research.
Chemical Information
| Catalog Num | A32772 |
|---|---|
| M. Wt | 378.38 |
| Formula | C21H18N2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3053861-26-7 |
| Synonyms | |
| SMILES | O=C1CCCC2=C1C(C3=CC=CC([N+]([O-])=O)=C3)C4=CC(OCCO5)=C5C=C4N2 |
Biological Activity
| Description | SSE1806 is a microtubule/tubulin inhibitor derived from podophyllotoxin, exhibiting notable anticancer and antiproliferative effects. It demonstrates a GI50 range of 1.29-21.15 μM against cancer cell growth, inducing mitotic abnormalities and G2/M phase cell cycle arrest. Additionally, SSE1806 enhances p53 expression and effectively inhibits the growth of colon cancer organoids, while also overcoming multidrug resistance in MDR-1 overexpressing cell lines, making it a valuable tool for cancer research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
