Product Data Sheet
Trametinib-13C,d3
Catalog No. A32809
Trametinib-13C,d3 is a stable isotope-labeled analog of Trametinib, a potent MEK1 and MEK2 inhibitor. With an IC50 of approximately 2 nM, Trametinib is known to activate autophagy and induce apoptosis in various cellular models. This labeled compound is ideal for use in metabolic studies, pharmacokinetic research, and tracer studies involving MEK signaling pathways.
Chemical Information
| Catalog Num | A32809 |
|---|---|
| M. Wt | 619.41 |
| Formula | C2513CH20D3FIN5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2712126-59-3 |
| Synonyms | GSK1120212-13C,d3; JTP-74057-13C,d3 |
| SMILES | CC(NC1=CC=CC(N(C(C(C(N2C3CC3)=O)=C(NC4=CC=C(I)C=C4F)N5C)=C([13C]([2H])([2H])[2H])C5=O)C2=O)=C1)=O |
Biological Activity
| Description | Trametinib-13C,d3 is a stable isotope-labeled analog of Trametinib, a potent MEK1 and MEK2 inhibitor. With an IC50 of approximately 2 nM, Trametinib is known to activate autophagy and induce apoptosis in various cellular models. This labeled compound is ideal for use in metabolic studies, pharmacokinetic research, and tracer studies involving MEK signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
