Product Data Sheet
PDIC-NN
Catalog No. A32814
PDIC-NN is a potent STING (Stimulator of Interferon Genes) activator that demonstrates significant anticancer activity. This compound enhances the stability and levels of endogenous cyclic dinucleotides (CDNs), triggering reactive oxygen species (ROS) production and inducing mitochondrial damage. Additionally, PDIC-NN promotes cell apoptosis and inhibits DNA replication while activating the cGAS-STING signaling pathway, thereby augmenting the immunogenicity of tumor cells and eliciting a robust innate immune response. This makes PDIC-NN a valuable tool for studying immune modulation and therapeutic strategies in cancer research.
Chemical Information
| Catalog Num | A32814 |
|---|---|
| M. Wt | 670.37 |
| Formula | C32H24Cl4N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 932740-48-2 |
| Synonyms | PDIC-NS free base |
| SMILES | O=C1C2=CC(Cl)=C3C4=C(C=C5C(N(CCN(C)C)C(C6=CC(Cl)=C(C4=C56)C7=C3C2=C(C(N1CCN(C)C)=O)C=C7Cl)=O)=O)Cl |
Biological Activity
| Description | PDIC-NN is a potent STING (Stimulator of Interferon Genes) activator that demonstrates significant anticancer activity. This compound enhances the stability and levels of endogenous cyclic dinucleotides (CDNs), triggering reactive oxygen species (ROS) production and inducing mitochondrial damage. Additionally, PDIC-NN promotes cell apoptosis and inhibits DNA replication while activating the cGAS-STING signaling pathway, thereby augmenting the immunogenicity of tumor cells and eliciting a robust innate immune response. This makes PDIC-NN a valuable tool for studying immune modulation and therapeutic strategies in cancer research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
