Product Data Sheet
NF023
Catalog No. A32867
NF023 is a selective inhibitor of X-BIR1/TAB1 assembly, impacting apoptosis by disrupting XIAP-mediated NF-κB activation. This compound modulates cell survival signaling pathways and demonstrates potential as a P2X1 adenylate receptor antagonist. NF023 may enhance the efficacy of pro-apoptotic therapies, offering a promising avenue for cancer treatment and suppression.
Chemical Information
| Catalog Num | A32867 |
|---|---|
| M. Wt | 1030.99 |
| Formula | C35H26N4O21S6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 99777-90-9 |
| Synonyms | |
| SMILES | O=C(NC1=CC=CC(C(NC2=CC=C(S(=O)(O)=O)C3=CC(S(=O)(O)=O)=CC(S(=O)(O)=O)=C23)=O)=C1)NC4=CC=CC(C(NC5=CC=C(S(=O)(O)=O)C6=CC(S(=O)(O)=O)=CC(S(=O)(O)=O)=C56)=O)=C4 |
Biological Activity
| Description | NF023 is a selective inhibitor of X-BIR1/TAB1 assembly, impacting apoptosis by disrupting XIAP-mediated NF-κB activation. This compound modulates cell survival signaling pathways and demonstrates potential as a P2X1 adenylate receptor antagonist. NF023 may enhance the efficacy of pro-apoptotic therapies, offering a promising avenue for cancer treatment and suppression. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
