Product Data Sheet
KY216
Catalog No. A32882
KY216 is a potent tubulin polymerization inhibitor that targets the colchicine-binding site of tubulin, with an IC50 value of 2.61 μM. This compound demonstrates significant biological activity in hindering tubulin polymerization, making it a valuable tool for research applications in non-small cell lung cancer (NSCLC) and breast cancer studies. KY216's mechanism of action positions it as a promising candidate for further investigation into therapeutic strategies against these malignancies.
Chemical Information
| Catalog Num | A32882 |
|---|---|
| M. Wt | 435.26 |
| Formula | C20H16Cl2N2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2804026-81-9 |
| Synonyms | Tubulin polymerization-IN-41 |
| SMILES | O=C(N1[C@@H](C2=CC3=C(C=C2C[C@H]14)OCCO3)C5=CC(Cl)=C(C(Cl)=C5)OC)NC4=O |
Biological Activity
| Description | KY216 is a potent tubulin polymerization inhibitor that targets the colchicine-binding site of tubulin, with an IC50 value of 2.61 μM. This compound demonstrates significant biological activity in hindering tubulin polymerization, making it a valuable tool for research applications in non-small cell lung cancer (NSCLC) and breast cancer studies. KY216's mechanism of action positions it as a promising candidate for further investigation into therapeutic strategies against these malignancies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
