Product Data Sheet
N-Oxide Lidocaine-d10
Catalog No. A32978
N-Oxide Lidocaine-d10 is a deuterium-labeled derivative of Lidocaine, which primarily targets voltage-gated sodium channels, inhibiting their activity in a complex, use-dependent manner. This compound exhibits significant biological activity, notably reducing the growth, migration, and invasion of gastric carcinoma cells by up-regulating miR-145 expression and subsequently inactivating the MEK/ERK and NF-κB signaling pathways. N-Oxide Lidocaine-d10 is valuable for research into ventricular arrhythmias and related cardiac applications.
Chemical Information
| Catalog Num | A32978 |
|---|---|
| M. Wt | 260.40 |
| Formula | C14H12D10N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 851528-10-4 |
| Synonyms | |
| SMILES | N(C(CN(C(C([2H])([2H])[2H])([2H])[2H])(C(C([2H])([2H])[2H])([2H])[2H])=O)=O)C1=C(C)C=CC=C1C |
Biological Activity
| Description | N-Oxide Lidocaine-d10 is a deuterium-labeled derivative of Lidocaine, which primarily targets voltage-gated sodium channels, inhibiting their activity in a complex, use-dependent manner. This compound exhibits significant biological activity, notably reducing the growth, migration, and invasion of gastric carcinoma cells by up-regulating miR-145 expression and subsequently inactivating the MEK/ERK and NF-κB signaling pathways. N-Oxide Lidocaine-d10 is valuable for research into ventricular arrhythmias and related cardiac applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
