Product Data Sheet
Antibacterial agent 292
Catalog No. A32990
Antibacterial Agent 292 is a 3-pyrazolylindole derivative targeting bacterial pathogens. This compound exhibits potent inhibitory activity against Xanthomonas oryzae pv oryzae (Xoo) and Xanthomonas axonopodis pv citri (Xac), with EC50 values of 2.54 and 3.49 μg/mL, respectively. It suppresses biofilm formation, bacterial motility, and extracellular polysaccharide production while inducing morphological changes and promoting ROS accumulation, leading to bacterial apoptosis. Additionally, it down-regulates genes associated with the type VI secretion system (T6SS), making it a valuable tool for research on rice bacterial blight and citrus canker.
Chemical Information
| Catalog Num | A32990 |
|---|---|
| M. Wt | 448.95 |
| Formula | C24H25ClN6O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3065015-86-0 |
| Synonyms | |
| SMILES | ClC1=CC=C(CN(CC2)CCN2CC(NC3=CC(C4=CNC5=C4C=CC=C5)=NN3)=O)C=C1 |
Biological Activity
| Description | Antibacterial Agent 292 is a 3-pyrazolylindole derivative targeting bacterial pathogens. This compound exhibits potent inhibitory activity against Xanthomonas oryzae pv oryzae (Xoo) and Xanthomonas axonopodis pv citri (Xac), with EC50 values of 2.54 and 3.49 μg/mL, respectively. It suppresses biofilm formation, bacterial motility, and extracellular polysaccharide production while inducing morphological changes and promoting ROS accumulation, leading to bacterial apoptosis. Additionally, it down-regulates genes associated with the type VI secretion system (T6SS), making it a valuable tool for research on rice bacterial blight and citrus canker. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
