Product Data Sheet
Kribb3
Catalog No. A33020
Kribb3 is a microtubule inhibitor that effectively disrupts microtubule dynamics. It demonstrates significant biological activity by inhibiting cancer cell proliferation with a GI50 range of 0.2-2.5 μM, promoting G2/M phase cell cycle arrest, and inducing apoptosis in HCT-116 cells. Additionally, Kribb3 has shown promising antitumor activity in murine models, making it a valuable tool for cancer research.
Chemical Information
| Catalog Num | A33020 |
|---|---|
| M. Wt | 325.36 |
| Formula | C19H19NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 129414-88-6 |
| Synonyms | |
| SMILES | OC1=CC(OC)=C(C=C1C2=C(C=NO2)C3=CC=C(C=C3)OC)CC |
Biological Activity
| Description | Kribb3 is a microtubule inhibitor that effectively disrupts microtubule dynamics. It demonstrates significant biological activity by inhibiting cancer cell proliferation with a GI50 range of 0.2-2.5 μM, promoting G2/M phase cell cycle arrest, and inducing apoptosis in HCT-116 cells. Additionally, Kribb3 has shown promising antitumor activity in murine models, making it a valuable tool for cancer research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
