Product Data Sheet
AB8939
Catalog No. A33108
AB8939 is a potent microtubule protein polymerization inhibitor that exhibits significant anti-tumor activity, with an IC50 of less than 10 nM against tumor cell proliferation. This compound effectively circumvents resistance mechanisms associated with P-glycoprotein and myeloperoxidase. AB8939 also induces G2/M phase cell cycle arrest and triggers apoptosis in affected cells, making it a valuable tool for cancer research and therapeutic development.
Chemical Information
| Catalog Num | A33108 |
|---|---|
| M. Wt | 392.45 |
| Formula | C22H24N4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1974336-09-8 |
| Synonyms | |
| SMILES | O=C1NCCN1C2=CC=C(C3=CN=C(NC4=CC(COCC)=CC=C4C)O3)C=C2 |
Biological Activity
| Description | AB8939 is a potent microtubule protein polymerization inhibitor that exhibits significant anti-tumor activity, with an IC50 of less than 10 nM against tumor cell proliferation. This compound effectively circumvents resistance mechanisms associated with P-glycoprotein and myeloperoxidase. AB8939 also induces G2/M phase cell cycle arrest and triggers apoptosis in affected cells, making it a valuable tool for cancer research and therapeutic development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
