Product Data Sheet

Cyclo(L-Phe-L-Pro)

Catalog No. A33188

main product photo
Cyclo(L-Phe-L-Pro) is an antifungal cyclic dipeptide that selectively targets the retinoic-acid-inducible gene-I (RIG-I) pathway, thereby inhibiting IFN-β production. Isolated from cell-free culture supernatants of Pseudomonas fluorescens and Pseudomonas alcaligenes, this compound demonstrates significant free-radical scavenging ability, with an IC50 of 24 µM in the DPPH assay. It serves as a valuable reagent in studies related to antifungal mechanisms and oxidative stress response.
Chemical Information
Catalog NumA33188
M. Wt244.29
FormulaC14H16N2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3705-26-8
Synonyms
SMILESO=C1N[C@@H](Cc2ccccc2)C(=O)N2CCC[C@@H]12
Biological Activity
DescriptionCyclo(L-Phe-L-Pro) is an antifungal cyclic dipeptide that selectively targets the retinoic-acid-inducible gene-I (RIG-I) pathway, thereby inhibiting IFN-β production. Isolated from cell-free culture supernatants of Pseudomonas fluorescens and Pseudomonas alcaligenes, this compound demonstrates significant free-radical scavenging ability, with an IC50 of 24 µM in the DPPH assay. It serves as a valuable reagent in studies related to antifungal mechanisms and oxidative stress response.
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