α-Hydroxyglutaric acid-d4 disodium
Catalog No. A33224

α-Hydroxyglutaric acid-d4 disodium is a stable isotope-labeled form of α-Hydroxyglutaric acid. This compound serves as a competitive inhibitor of various α-ketoglutarate-dependent dioxygenases, including histone demethylases and TET enzymes involved in 5-methylcytosine hydroxylation. Its unique labeling facilitates quantitative studies and metabolic tracing in research applications related to epigenetics and metabolism.
Chemical Information
| Catalog Num | A33224 |
|---|---|
| M. Wt | 196.10 |
| Formula | C5H2D4Na2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2483831-91-8 |
| Synonyms | 2-Hydroxyglutarate-d4 disodium; 2-Hydroxyglutaric acid-d4 disodium; 2-Hydroxypentanedioic acid-d4 disodium |
| SMILES | O=C(O[Na])CC([2H])([2H])C(O[2H])([2H])C(O[Na])=O |
Biological Activity
| Description | α-Hydroxyglutaric acid-d4 disodium is a stable isotope-labeled form of α-Hydroxyglutaric acid. This compound serves as a competitive inhibitor of various α-ketoglutarate-dependent dioxygenases, including histone demethylases and TET enzymes involved in 5-methylcytosine hydroxylation. Its unique labeling facilitates quantitative studies and metabolic tracing in research applications related to epigenetics and metabolism. |
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RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


