Product Data Sheet

(R)-9b

Catalog No. A33246

main product photo
(R)-9b is a potent inhibitor of ACK1 tyrosine kinase, exhibiting an IC50 value of 56 nM. This compound selectively targets ACK1 while also exhibiting inhibitory effects on JAK2 and Tyk2 kinases. (R)-9b is valuable for research into hormone-regulated cancers, including prostate and breast cancer, providing a tool for understanding ACK1's role in cancer progression and treatment.
Chemical Information
Catalog NumA33246
M. Wt402.92
FormulaC20H27ClN6O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1655527-68-6
Synonyms
SMILESCN1CCN(C2=CC=C(NC3=NC=C(Cl)C(NC[C@@H]4OCCC4)=N3)C=C2)CC1
Biological Activity
Description(R)-9b is a potent inhibitor of ACK1 tyrosine kinase, exhibiting an IC50 value of 56 nM. This compound selectively targets ACK1 while also exhibiting inhibitory effects on JAK2 and Tyk2 kinases. (R)-9b is valuable for research into hormone-regulated cancers, including prostate and breast cancer, providing a tool for understanding ACK1's role in cancer progression and treatment.
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