Product Data Sheet
JAK1-IN-8
Catalog No. A33267
JAK1-IN-8 is a potent inhibitor of Janus kinase 1 (JAK1) with an IC50 of less than 500 nM. This compound demonstrates significant inhibition of JAK1-mediated signaling pathways, making it a valuable tool for studying immune responses and inflammatory conditions. Its application extends to research in cancer biology and other diseases where JAK1 plays a critical role in pathophysiology.
Chemical Information
| Catalog Num | A33267 |
|---|---|
| M. Wt | 442.51 |
| Formula | C22H23FN4O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1973485-18-5 |
| Synonyms | |
| SMILES | O=C(C1CC1)NC2=CN3C(C4=CC(F)=C(CN5CCS(=O)(CC5)=O)C=C4)=CC=CC3=N2 |
Biological Activity
| Description | JAK1-IN-8 is a potent inhibitor of Janus kinase 1 (JAK1) with an IC50 of less than 500 nM. This compound demonstrates significant inhibition of JAK1-mediated signaling pathways, making it a valuable tool for studying immune responses and inflammatory conditions. Its application extends to research in cancer biology and other diseases where JAK1 plays a critical role in pathophysiology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
