Product Data Sheet
(2R,5S)-Ritlecitinib
Catalog No. A33276
(2R,5S)-Ritlecitinib is a selective inhibitor of Janus kinase 3 (JAK3) with an IC50 of 144.8 nM. This compound demonstrates significant biological activity in modulating immune responses and is primarily utilized in research focused on autoimmune diseases and hematological disorders. Its ability to inhibit JAK3 signaling pathways makes it a valuable reagent for studies investigating cytokine signaling and immunological reactions.
Chemical Information
| Catalog Num | A33276 |
|---|---|
| M. Wt | 285.35 |
| Formula | C15H19N5O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1792180-79-0 |
| Synonyms | (2R,5S)-PF-06651600 |
| SMILES | C[C@@H]1CC[C@@H](CN1C(C=C)=O)NC2=C3C=CNC3=NC=N2 |
Biological Activity
| Description | (2R,5S)-Ritlecitinib is a selective inhibitor of Janus kinase 3 (JAK3) with an IC50 of 144.8 nM. This compound demonstrates significant biological activity in modulating immune responses and is primarily utilized in research focused on autoimmune diseases and hematological disorders. Its ability to inhibit JAK3 signaling pathways makes it a valuable reagent for studies investigating cytokine signaling and immunological reactions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
