Product Data Sheet
JAK-IN-10
Catalog No. A33302
JAK-IN-10 is a selective Janus kinase (JAK) inhibitor that modulates inflammatory pathways by inhibiting JAK signaling. It is particularly valuable in the study of dry eye disorders, providing insights into the underlying mechanisms of inflammation. Additionally, JAK-IN-10 features an alkyne functional group and is suitable for click chemistry applications, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing compounds. This property enhances its utility in chemical biology and medicinal chemistry research.
Chemical Information
| Catalog Num | A33302 |
|---|---|
| M. Wt | 427.45 |
| Formula | C20H18FN5O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 916741-98-5 |
| Synonyms | |
| SMILES | O=S(C1=CC(NC2=NC=C(F)C(NC3=CC=C(OCC#C)C=C3)=N2)=CC=C1C)(N)=O |
Biological Activity
| Description | JAK-IN-10 is a selective Janus kinase (JAK) inhibitor that modulates inflammatory pathways by inhibiting JAK signaling. It is particularly valuable in the study of dry eye disorders, providing insights into the underlying mechanisms of inflammation. Additionally, JAK-IN-10 features an alkyne functional group and is suitable for click chemistry applications, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing compounds. This property enhances its utility in chemical biology and medicinal chemistry research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
