Product Data Sheet

Tyk2-IN-8

Catalog No. A33314

main product photo
Tyk2-IN-8 is a selective inhibitor of Tyk-2, exhibiting an IC50 of 5.7 nM for TYK2-JH2 and 3.0 nM for JAK1-JH1. This compound is instrumental in investigating the role of Tyk-2 in various biological processes. Tyk2-IN-8 is particularly relevant for research focused on autoimmune diseases, enabling studies on signaling pathways involved in immune regulation and inflammation.
Chemical Information
Catalog NumA33314
M. Wt425.46
FormulaC20H19D3N8O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2704587-24-4
Synonyms
SMILES[2H]C([2H])([2H])OC1=C(C2=NN(C)C=N2)C=CC=C1NC3=C(N=NC(NC(C4CC4)=O)=C3)C(NC)=O
Biological Activity
DescriptionTyk2-IN-8 is a selective inhibitor of Tyk-2, exhibiting an IC50 of 5.7 nM for TYK2-JH2 and 3.0 nM for JAK1-JH1. This compound is instrumental in investigating the role of Tyk-2 in various biological processes. Tyk2-IN-8 is particularly relevant for research focused on autoimmune diseases, enabling studies on signaling pathways involved in immune regulation and inflammation.
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SHIPPING AND STORAGE
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