Product Data Sheet
Peficitinib hydrobromide
Catalog No. A33321
Peficitinib hydrobromide is a selective Janus kinase (JAK) inhibitor, exhibiting IC50 values of 3.9 nM for JAK1, 5.0 nM for JAK2, 0.7 nM for JAK3, and 4.8 nM for Tyk2. This compound is primarily utilized in research related to autoimmune diseases and inflammatory conditions, demonstrating potential therapeutic efficacy in modulating immune responses. Its oral bioavailability makes it a valuable tool for studying JAK signaling pathways in various biological models.
Chemical Information
| Catalog Num | A33321 |
|---|---|
| M. Wt | 407.30 |
| Formula | C18H23BrN4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1353219-05-2 |
| Synonyms | ASP015K hydrobromide; JNJ-54781532 hydrobromide |
| SMILES | O[C@](C[C@@H]1C[C@H]2C3)(C2)C[C@@H]3[C@H]1NC4=C5C(NC=C5)=NC=C4C(N)=O.Br[H] |
Biological Activity
| Description | Peficitinib hydrobromide is a selective Janus kinase (JAK) inhibitor, exhibiting IC50 values of 3.9 nM for JAK1, 5.0 nM for JAK2, 0.7 nM for JAK3, and 4.8 nM for Tyk2. This compound is primarily utilized in research related to autoimmune diseases and inflammatory conditions, demonstrating potential therapeutic efficacy in modulating immune responses. Its oral bioavailability makes it a valuable tool for studying JAK signaling pathways in various biological models. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
