Product Data Sheet
Peficitinib hydrochloride
Catalog No. A33347
Peficitinib hydrochloride is a selective Janus kinase (JAK) inhibitor that effectively targets JAK1, JAK2, JAK3, and Tyk2, with IC50 values of 3.9 nM, 5.0 nM, 0.7 nM, and 4.8 nM, respectively. This compound is primarily used in research to investigate JAK-dependent signaling pathways and for studies related to inflammatory and autoimmune diseases. Its potent inhibitory activity makes it a valuable tool for exploring therapeutic options against conditions such as rheumatoid arthritis and psoriasis.
Chemical Information
| Catalog Num | A33347 |
|---|---|
| M. Wt | 362.85 |
| Formula | C18H23ClN4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1353219-06-3 |
| Synonyms | ASP015K hydrochloride; JNJ-54781532 hydrochloride |
| SMILES | O[C@](C[C@@H]1C[C@H]2C3)(C2)C[C@@H]3[C@H]1NC4=C5C(NC=C5)=NC=C4C(N)=O.Cl |
Biological Activity
| Description | Peficitinib hydrochloride is a selective Janus kinase (JAK) inhibitor that effectively targets JAK1, JAK2, JAK3, and Tyk2, with IC50 values of 3.9 nM, 5.0 nM, 0.7 nM, and 4.8 nM, respectively. This compound is primarily used in research to investigate JAK-dependent signaling pathways and for studies related to inflammatory and autoimmune diseases. Its potent inhibitory activity makes it a valuable tool for exploring therapeutic options against conditions such as rheumatoid arthritis and psoriasis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
